https://github.com/petertodd/python-bitcoinlib/tree/python-bitcoinlib-v0.5.0rc1
FWIW if you've been experienceing OpenSSL related crashes on OSX or Arch Linux this release should fix your issues. I don't have any way of testing this myself, so if I could get some confirmation that this new release candidate fixes things that'd be really helpful!
Other release notes:
v0.5.0 ======
Major fix: Fixed OpenSSL related crashes on OSX and Arch Linux. Big thanks to everyone who helped fix this!
Breaking API changes:
* Proxy no longer has ``__getattr__`` to support arbitrary methods. Use
RawProxy or Proxy.call instead. This allows new wrappers to be added safely.
See docstrings for details.
New features:
* New RPC calls: getbestblockhash, getblockcount, getmininginfo
* Signing and verification of Bitcoin Core compatible messages. (w/ pubkey recovery)
* Tox tests
* Sphinx docs
Notable bugfixes:
* getinfo() now works where disablewallet=1